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Sebastiaan Overeem Selected Research

Sleep Wake Disorders

1/2021Sleep disorders and the hypothalamus.
11/2018Enhanced food-related responses in the ventral medial prefrontal cortex in narcolepsy type 1.
5/2016Pandemic influenza vaccine & narcolepsy: simulations on the potential impact of bias.
12/2012Association between hypocretin-1 and amyloid-β42 cerebrospinal fluid levels in Alzheimer's disease and healthy controls.
8/2012Hypocretin (orexin) loss in Alzheimer's disease.
4/2012Altered circadian rhythm of melatonin concentrations in hypocretin-deficient men.
9/2010Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
2/2009Hypocretin/orexin disturbances in neurological disorders.
5/2005Altered setting of the pituitary-thyroid ensemble in hypocretin-deficient narcoleptic men.
4/2003Screening for anti-ganglioside antibodies in hypocretin-deficient human narcolepsy.
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Sebastiaan Overeem Research Topics

Disease

42Narcolepsy
12/2022 - 10/2002
15Cataplexy
12/2022 - 10/2002
13Sleep Wake Disorders
01/2021 - 10/2002
8Disorders of Excessive Somnolence (Hypersomnia)
12/2022 - 10/2002
7Parkinson Disease (Parkinson's Disease)
01/2014 - 10/2002
6Alzheimer Disease (Alzheimer's Disease)
01/2020 - 08/2012
5Obesity
11/2016 - 09/2003
4Sleep Initiation and Maintenance Disorders (Insomnia)
01/2021 - 10/2002
2Sleep Deprivation
01/2021 - 08/2014
2Dementia (Dementias)
01/2019 - 08/2012
2Human Influenza (Influenza)
10/2018 - 05/2016
2Obstructive Sleep Apnea
06/2017 - 10/2002
2Body Weight (Weight, Body)
08/2013 - 03/2003
2Nervous System Diseases (Neurological Disorders)
02/2009 - 10/2002
1Atrophy
01/2019
1Cognitive Dysfunction
01/2019
1Central Sleep Apnea (Central Sleep Apnea Syndrome)
01/2018
1REM Sleep Behavior Disorder
10/2017
1Anosmia
10/2017
1Intellectual Disability (Idiocy)
06/2017
1Insulin Resistance
04/2014
1Weight Loss (Weight Reduction)
04/2014
1Psychological Trauma
09/2013
1Hallucinations (Hallucination)
09/2013
1Respiratory Sounds (Crackle)
01/2011
1Fasciculation (Fasciculations)
01/2010
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2009
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
10/2009
1Huntington Disease (Huntington's Disease)
10/2008
1Abdominal Obesity
09/2003
1Guillain-Barre Syndrome
04/2003
1Restless Legs Syndrome (Restless Legs)
10/2002
1Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
10/2002
1Prader-Willi Syndrome (Syndrome, Prader-Willi)
10/2002

Drug/Important Bio-Agent (IBA)

38OrexinsIBA
12/2022 - 10/2002
7Sodium Oxybate (gamma Hydroxybutyrate)FDA Link
01/2016 - 03/2011
4Biomarkers (Surrogate Marker)IBA
01/2022 - 06/2014
3HLA-DQB1 antigen (HLA DQB1)IBA
12/2021 - 10/2002
3Polymethyl Methacrylate (Sol)IBA
01/2021 - 01/2019
3Amyloid (Amyloid Fibrils)IBA
01/2020 - 08/2014
3VaccinesIBA
10/2018 - 02/2013
2Proteins (Proteins, Gene)FDA Link
01/2020 - 08/2014
2pandemrixIBA
10/2018 - 05/2016
2Biological ProductsIBA
02/2017 - 10/2002
2Pharmaceutical PreparationsIBA
10/2015 - 01/2014
2MelatoninIBA
01/2013 - 04/2012
2Growth Hormone (Somatotropin)IBA
06/2011 - 03/2003
1Dopamine (Intropin)FDA LinkGeneric
11/2022
1solriamfetolIBA
11/2022
1Norepinephrine (Noradrenaline)FDA LinkGeneric
11/2022
1zopiclone (Zop)IBA
01/2021
14-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
01/2019
1NeuropeptidesIBA
11/2018
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
10/2017
1Influenza Vaccines (Influenza Vaccine)FDA Link
05/2016
1HLA-DPB1 antigen (HLA DPB1)IBA
03/2016
1HLA-A Antigens (HLA-A)IBA
03/2016
1Glucose (Dextrose)FDA LinkGeneric
04/2014
1Glycerol (Glycerine)FDA LinkGeneric
04/2014
1Insulin (Novolin)FDA Link
04/2014
1Transcription Factors (Transcription Factor)IBA
10/2013
1Hydrocortisone (Cortisol)FDA LinkGeneric
09/2013
1N-(4-aminophenethyl)spiroperidol (NAPS)IBA
09/2013
1Therapeutic UsesIBA
09/2013
1Hormones (Hormone)IBA
08/2013
1LeptinIBA
08/2013
1GhrelinIBA
08/2013
1propylene diquat (PDQ(+))IBA
05/2013
1OX40 LigandIBA
01/2013
1Cathepsin HIBA
01/2013
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2013
1Neurotransmitter Agents (Neurotransmitter)IBA
08/2012
1Adrenocorticotropic Hormone (ACTH)FDA Link
03/2011
1ProlactinIBA
03/2011
1HLA Antigens (Human Leukocyte Antigens)IBA
09/2010
1HLA-DRB1 Chains (HLA DRB1)IBA
09/2010
1Caffeine (No Doz)FDA LinkGeneric
01/2010
1melanin-concentrating hormone (melanin concentrating hormone)IBA
10/2008
1AutoantibodiesIBA
05/2006
1AntigensIBA
04/2003
1GangliosidesIBA
04/2003
1AntibodiesIBA
04/2003
1Psychotropic Drugs (Psychoactive Drugs)IBA
10/2002
1HLA-DQ Antigens (HLA-DQ)IBA
10/2002

Therapy/Procedure

4Therapeutics
01/2018 - 10/2003
2Continuous Positive Airway Pressure
06/2017 - 01/2011
2Institutionalization (Institutionalized Persons)
12/2014 - 08/2012
1Aftercare (After-Treatment)
04/2014
1Activities of Daily Living (ADL)
10/2013
1Tracheotomy
01/2011